Plug-and-play: The Digest’s 2017 Multi-Slide Guide to Enzyme Engineering and Optimization


The US Department of Energy is supporting a project led by Michael Himmell at the National Renewable Energy Laboratory to develop technology to meet or exceed the target of 10 mg/g cellulose on pretreated feedstocks and feedstock blends. Attainment of this overall enzyme cost is consistent with BETO’s techno-economic evaluations for the 2022 biomass conversion target.

The team aims for metabolic enzyme improvement and development of plug-and-play pathway engineering techniques — and to improve existing and enable new metabolic pathways.

Michael Himmell prepped these illuminating slides on the project’s progress and promise for the DOE’s Project peer Review meetings.