Yousong Ding and colleagues at the University of Florida inserted genes responsible for shinorine production in filamentous cyanobacterium Fischerella and inserted them into fast-growing cyanobacteria Synechocystis. They then focused on boosting production by adding promoters to the gene cluster.
Synthetic sunscreen ingredients have been implicated in disrupting hormones in aquatic environments. Shinorine has been eyed as a viable alternative, but relies on seasonal growth of red algae.
The work was published in a recent issue of ACS Synthetic Biology.