The Digest’s 2025 Multi-Slide Guide to Praio

Praio is commercializing patented artificial Protocells for intensified biomanufacturing, merging the advantages of whole-cell efficiency and cell-free flexibility. This platform improves reaction rates >10x and is stable over four months. The technology has demonstrated 1L scale continuous processing. Praio is strategically targeting high-margin specialty chemicals (sweeteners/fragrances) as its first product, aiming to transition later to large-scale commodities like biofuels (e.g., ethanol-to-butanol) and build an Advanced Biorefinery. Scale-up is planned utilizing the ABPDU’s 300L infrastructure.