NREL grants Crysalis commercial licenses to three novel techs for biofuels and chemicals

June 4, 2025 |

In Colorado, based on research initially funded by DOE’s Bioenergy Technologies Office, NREL granted Crysalis commercial licenses to three novel biological technologies to produce bio-based chemicals and fuels, including:

·      2,3-Butanediol (2,3-BDO): This technology leverages a modified strain of Zymomonas mobilis to produce 2,3-BDO instead of ethanol, which can be used to produce polymers and butadiene, a key ingredient in bio-derived rubber for tires.

·      Carboxylic Acids to Aviation Fuel: This process converts America’s plentiful sources of waste and biomass into carboxylic acids, which can be upgraded to a jet fuel blendstock, serving as an abundant energy source for export and the domestic aviation industry.

·      Acetonitrile: This process allows for the production of ultrahigh purity acetonitrile, a high-demand solvent in pharmaceutical manufacturing, as well as other high-performance, high-volume materials like advanced batteries.

The licensing of these three technologies showcases how the NREL/Crysalis partnership can leverage America’s plentiful biomass and waste feedstocks—more than 1 billion tons according to a recent DOE study—to drive homegrown production of critical materials and agricultural products the country needs and reduce its reliance on imports.

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Category: Fuels

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